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While earlier GLP-1 drugs have decades of data behind them, newer high-potency agonists and multi-agonist combinations will require extended monitoring as their use expands

these drugs include glucagon-like peptide-1 (GLP-1) receptor agonists and dipeptidyl peptidase 4 (DPP-4) inhibitors [13, 14]

What are the most common adverse reactions, and which ones require immediate medical attention

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While FDA-approved branded medications like Wegovy and Zepbound have demonstrated efficacy in controlled clinical trials, many patients still face substantial out-of-pocket expenses