2011, titled Contributions of serotonin in addiction vulnerability, shows low serotonin levels are significant predictive factors in identifying vulnerability to addiction
however, it is recommended that individuals with sensitive skin or scalp should perform a patch test prior to regular application
In gastrointestinal research, a 2017 rat colitis and ischemia-reperfusion study by Duzel and colleagues in World Journal of Gastroenterology reported that a single 10 g/kg topical bath of BPC-157 to blood-deprived colon segments produced near-complete mucosal preservation by day 10, restored vessel-arcade interconnections, and normalized MDA and NO levels relative to saline controls though the abstract does not report numeric % lesion reduction or p-values
BPC-157 and TB-500 capsules are easy to take, eliminating the need for injections or nasal administration
Tirzepatide does not go from 100 percent potent to zero overnight
doi: 10.1073/pnas.1207169109 116 GoreACThompsonLMBellMMennigenJA