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Signs that you should pause escalation include persistent nausea lasting more than 3 days after injection, vomiting more than once per week, diarrhea that interferes with daily activities, or significant appetite loss that makes it difficult to consume adequate protein and nutrients

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[1] [2] This extended room temperature tolerance for in-use pens recognises that patients need practical access to their medication and may not always have immediate refrigeration available

Additionally, they exert a neuroprotective effect independently of blood glucose levels ( Table 2 )

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