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Materials 15 (17), 6039

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It activates AMPK (AMP-activated protein kinase), the same metabolic sensor that metformin targets, which explains the overlapping effects

Z-His(Boc)-D-Phe-Arg(HCl)-Trp-Lys( Boc)-NH 2 ( 9 ) A solution of tetrapeptide hydrochloride 8 (34 g, 44.1 mmol) in methanol was added to Z-His( T Boc)-OPfp (22.2 g, 48.8 mmol)

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