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More recently, the combination of GLP-1 Ras with GCG RA or with GIP RA in NASH murine models allowed one to achieve additional weight loss and, more importantly, to determine a greater improvement in histological NAFLD activity score compared to treatment with mono-agonists [172]

We also closely monitor thyroid function in patients with existing thyroid disorders and assess the impact of renal impairment on treatment suitability

Liver and nervous system The liver plays a role in controlling energy supply during fasting and, when fat metabolism does not function normally, general symptoms may arise

The Anorectic Effect of GLP-1 in Rats Is Nutrient Dependent

Modulation of chronic inflammation by quercetin: the beneficial effects on obesity