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These markers are useful when symptoms or risk factors suggest a functional deficiency that a high total B12 could be masking

And its not surprising that a deficiency can cause significant health issues

The recommended dietary allowance for adults is 2.4 micrograms per day according to the NIH Office of Dietary Supplements (updated 2025)

(More information) Low maternal vitamin B 12 status has been associated with an increased risk of neural tube defects (NTD), but it is not known whether vitamin B 12 supplementation could help reduce the risk of NTD

They are sold legally under the research use only labels, which means they are permitted for laboratory study but cannot be legally marketed for human consumption, diagnosis, or treatment

Everything was very clean and sterile