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To date, these described environmental animal models (ABA and SBA) remain the only models that enable long term studies of how chronic food restriction impacts upon physiology at different levels (energy balance, reproduction, bone/fat regulation, etc.), and of the mechanisms responsible for the sustenance of these alterations on different tissues often not available on patients (brain, bones, fat, muscle, liver, etc.)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 103.Yang J., Ruchti E., Petit J., Jourdain P., Grenningloh G., Allaman I., Magistretti P.J

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It also reduces inflammation and supports liver health