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Metformins action is based on minimizing hepatic glucose synthesis and raising peripheral sensitivity to circulating insulin (138)

If recurrent genital thrush persists, review any concomitant SGLT2 inhibitor therapy, as these medications (unlike GLP-1 receptor agonists) are associated with increased risk of genital mycotic infections

Adults with a body mass index (BMI) above 30 are eligible to be prescribed semaglutide for weight loss treatment