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For a broader landscape of what is and is not well-supported, see our overview of the most-studied peptides

PMID: 9384660

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However, the most worrying are the long-term adverse effects that have been described, such as an increase in cardiovascular complications, the development of T2D, and different types of cancer, which is why its application in real life as an antiaging therapy continues to be controversial and requires further studies to define the stage in life in which it would be most useful, the optimal time of use, and ways of monitoring and preventing its adverse effects

How fast tirzepatide works and how long it takes tirzepatide to work provide realistic expectation-setting that improves adherence