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This highlights the need to consider gut microbial balance when evaluating prolonged PPI therapy

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This principle was also explored by scientists at Affibody, who showed that the alternative molecular scaffold of affibodies could be expressed as a fusion protein with an albumin-binding domain and used to prevent IgG binding to FcRn both in vitro and in WT mice (i.e., mice expressing native mouse FcRn) [125]

LRP1 is an extracellular subunit that consists of four ligand-binding domains (DI, DII, DIII, and DIV) and repeat epidermal growth factor (EGF) [39]