VEGF expression is upregulated in the hyperplastic epidermis of psoriasis (17), in healing wounds (18), and in other skin diseases characterized by enhanced angiogenesis (19, 20), and targeted overexpression of VEGF in the epidermis of transgenic mice resulted in enhanced skin vascularization with increased numbers of tortuous and leaky blood vessels (21)
Topiramate works on different brain chemicals, which can provide an additional layer of suppression for those whose food noise is tied to neurological triggers or compulsive habits
When the medication ceases, this adaptation lingers, facilitating the rebound of pounds
"Once-Weekly Semaglutide in Adults with Overweight or Obesity." NEJM
BPC-157 appears to improve both aspects of collagen quality
Shannon CE, Nixon AV, et al