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The significance of IGF-IR in BrCa is further supported by the observation that absent or severely reduced IGF-1R expression leads to non-viable MCF7 cells after a few tissue culture passages [90]

Curr Opin Cell Biol 15:247254 Smythies J (1999) The neurotoxicity of glutamate, dopamine, iron and reactive oxygen species: functional interrelationships in health and disease: a reviewdiscussion

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