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It causes disruption of the blood-brain barrier (BBB), infiltration of peripheral blood cells, oxidative stress, neuroinflammation and apoptosis, neural excitotoxicity, and mitochondrial dysfunction

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A clear scientific overview of the broader ghrelin/GHS system is available in this NIH/PMC review (Veldhuis & Roelfsema, 2010)

It has been utilized in the treatment of various conditions, including sinusitis, bronchitis, and sinus infections