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doi: 10.1186/s40478-025-02013-z 119 YangXLiuHYeTDuanCLvPWuXet al

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A widely cited microarray screen reported that GHK exposure of human fibroblast cultures altered expression of more than 4,000 genes, with pathway analysis identifying TGF-, integrin, and ubiquitin-proteasome signaling as enriched among GHK-responsive transcripts

The blend is not approved for human use Tesamorelin alone is FDA-approved as EGRIFTA for HIV-associated lipodystrophy, while Ipamorelin is not FDA-approved for any indication

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