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The GLP-1RA semaglutide consistently reduced MACE risk across eGFR and UACR subgroups, indicating that semaglutide provides CV benefits in people with T2D and at high CV risk across a broad spectrum of kidney function and damage

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it was developed in 1995 and approved for marketing in 2005.60 Liraglutide was subsequently approved for marketing in February 2010,62 and lixisenatide was approved for marketing in the European Union in 2013 for the treatment of T2DM and in the United States in July 2016.63 Albiglutide was approved for marketing in the European Union in March 2014 and in the United States in April 2014.64 Dulaglutide was approved for marketing in the U.S

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