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Furthermore, clinically meaningful blood pressure reductions were observed in participants receiving TZP

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Unlike earlier GH secretagogues, ipamorelin exhibits high selectivity, minimal activity at other hormonal axes (ACTH, cortisol, or prolactin), and potent GH release in both animals and humans

JAMA 2022;327:534-45.ArticlePubMedPMC 129

Glycosaminoglycans, dermatan sulfate, and chondroitin sulfate production also rise, collectively rebuilding the hydrated, resilient matrix characteristic of younger tissue