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Recommended Dosage of Glutathione for Skin Support Based on available clinical studies and standard nutritional practice, here are the dosage guidelines: General skin support and antioxidant defence: 250mg per day Targeted skin radiance support: 500mg per day Upper range (under practitioner guidance): 500-1000mg per day How to Take It Take on an empty stomach ideally 30 minutes before breakfast or 2 hours after dinner Pair with Vitamin C (500-1000mg) to support glutathione recycling Stay consistent daily supplementation is important for building and maintaining levels Drink adequate water throughout the day Is It Safe for Long-Term Use