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A 2017 study found that the drug improved insulin sensitivity in the heart by 75%, augmented insulin sensitivity in skeletal muscle tissue by 71% and increased both cardiac ejection fraction and coronary blood flow by more than 10%

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Early concerns that glucagon activation might raise blood sugar or interfere with muscle building proved unfounded when combined with GLP-1 activity

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For patients undergoing elective dental procedures under sedation, the practitioner must obtain a detailed medical history and updated medication list prior with special consideration for those who take GLP-1 agonists