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The need for emergency surgery, with its attendant risks, recovery time, lost wages, and permanent digestive changes after gallbladder removal, impacts quality of life and creates substantial economic damages

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Pharmacologic treatment may include diaxozide nifedipine octreotide glucocorticoids glucagon In refractory patients, reversal of gastric bypass or subtotal or near total pancreatectomy can be considered.

Zerweck, J