A powerful Anti-Inflammatory and Antioxidant
This reduction in risk is likely largely due to weight loss, which is itself an important finding
"Tirzepatide versus Insulin Glargine in Type 2 Diabetes and Increased Cardiovascular Risk (SURPASS-4): A Randomised, Open-Label, Parallel-Group, Multicentre, Phase 3 Trial." The Lancet, 2021, 398(10313), 1811-1824
TXNIP-induced ROS production further amplifies apoptotic signaling and activates inflammasomes (52,180)
The very first of these was No-Cal Ginger Ale, a sugar-free soft drink created by Russian immigrant and businessman Hyman Kirsch, who wanted to sell a drink that could be enjoyed by the diabetic patients at the Jewish Sanitarium for Chronic Disease, where Kirsch was vice president
Hilton C, Neville MJ, Karpe F