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In this study we investigated the effect of GLP-1R agonist liraglutide on blood pressure, hydration status, natriuresis and the activity of the reninangiotensinaldosterone axis in patients with diabetic kidney disease after a dose of liraglutide compared to placebo

While this study offers valuable insights, it also underscores the need for further research to explore additional outcomes beyond weight loss

Clinical trials show an average weight loss of around 21%

C., & Malalgoda, M

Research shows that weight regain occurs in approximately 50-70% of patients within one year of stopping GLP-1 therapy, making the transition off medication a critical clinical consideration

*Correspondence: Joo Sargento-Freitas [email protected] This article was submitted to Stroke, a section of the journal Frontiers in Neurology These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers