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Kneeling supporting your body through your hands or forearms and knees is another helpful position for shifting gas and relieving discomfort, but only when your body feels comfortable in this position

The recommended schedule from clinical trials is: Weeks 1-4: 2.5 mg once weekly Weeks 5-8: 5 mg once weekly Weeks 9-12: 7.5 mg once weekly Weeks 13-16: 10 mg once weekly Weeks 17-20: 12.5 mg once weekly Week 21+: 15 mg once weekly (maximum dose) Not everyone follows this exact schedule

The cost can still be hundreds of dollars a month

J Pharm Technol 38:239246

Peak concentrations drive maximal receptor occupancy and maximal metabolic demand

The same documentation principle applies