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However, the SF-36 scores, PHES scores, normalization rate of minimal HE, and rate-correct scores on the Stroop test at week 24 did not differ between the two groups

Conversely, IR contributes to reduced dopamine transporter expression coupled with increased excitatory glutamatergic input, elevating extracellular dopamine levels

UN: Conceptualization, Project administration, Supervision, Validation, Writing original draft, Writing review & editing

[Accessed on 11 June 2026] Q4 2025 / Full Year 2025 Investor Presentation

Cagrilintide is the first long-acting amylin analog to reach Phase 3 trials, with fatty acid acylation enabling once-weekly dosing compared to the three-times-daily dosing required by the older amylin analog pramlintide