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Although these approaches have superior long-term weight loss results, patients are at high risk of vitamin B malabsorption following bariatric surgery (Table 2)

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BPC-157, by contrast, operates largely through modulation of the nitric oxide (NO) system and upregulation of growth factor expression, including VEGF and EGF, supporting angiogenesis and granulation tissue formation

The proposed mechanism involves maintaining synaptic vesicle integrity, competing for receptor sites, and potentially substituting for depleted neurotransmitters