"So it's another piece of the pie, another proof of evidence that the semaglutide is working on those systems in the brain that we know are important for addiction." Leggio is now working on a protocol for a randomized controlled trial that will look at semaglutide and alcohol use in humans and collaborating with Oklahoma State University on a similar study
Frequently Asked Questions Can I get pregnant while taking semaglutide
Accessed November 13, 2025
This leads to reduced hunger, increased feelings of fullness (satiety), and consequently decreased caloric intake
As the therapeutic landscape continues to evolve with the advent of even more potent agents like the dual-agonist tirzepatide, the role of semaglutide will continue to be refined
However, recently, a superior effect of triple agonists has been indicated, with triple agonists providing a greater neuroprotective benefit against glutamate excitotoxicity compared with dual receptor agonists [126]