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Stop GLP-1 RAs or tirzepatide if BMI drops below 18.5 kg/m

While these medications are generally well-tolerated, clinicians and patients should be aware of both common and serious adverse effects

The risk of hypoglycemia increases when you use the medication with other diabetes medications such as sulfonylureas and insulin

Individuals with specific polymorphisms may show different appetite-suppression responses to equivalent semaglutide doses

In research, weight loss improved insulin sensitivity and fertility, both of which are common PCOS symptoms

Drug manufacturers design subcutaneous medications knowing that patients will use different injection sites, and they ensure the therapeutic window is wide enough to accommodate these normal variations