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Research suggests evening administration reduces perceived nausea and vomiting in up to 20% of patients, specifically because these gastrointestinal effects hit during sleep rather than waking hours

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Specifically, among treatment agent, Schisandrin C demonstrated the largest effect size with concomitant reduction in heterogeneity [SMD = 7.52, 95% CI (10.13, 4.91), I 2 = 0.0%, p = 0.579]

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