4A and 4B, treatment with 1000 FAC markedly decreased the cell viability and increased cell death in primary hepatocytes
Magnesium also plays an important role in managing cortisol, the body's primary stress hormone
Importantly, it has been reported that the effects can be exacerbated when the exposed individuals are already obese [7]
In the case of alcohol the mechanism is well described: ethanol metabolism involving the CYP2E1 enzyme releases free radicals, and these reduce the level of reduced glutathione in the liver (Lieber, Drug Metabolism Reviews 2004, PMID 15554233)
Researchers continue exploring how these pathways contribute to overall metabolic science
Dr Paul Chee, Dermatologist and Director of Dermatology, John Hunter Hospital and Royal Newcastle Centre, Newcastle, Australia