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Allosteric modulators Allosteric modulators typically attach to regions distinct from the orthosteric site of receptors, inducing conformational changes to regulate the affinity and/or efficacy of orthosteric ligands, or to directly modulate receptor activity with positive, negative, or neutral effects
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These lawsuits are highly influential in the practice of urban planning leading to its increasing exposure to judicial overview and decisions, excluding planners, elected officials and urban citizens
40 1-2
L- , : L- 500-2000
G., Sheppard, H
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