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Patients with CKD who progress to ESRD require renal replacement therapies, such as PD and HD [159, 160]
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A single ascending dose, first-in-human phase 1 study to assess the safety and pharmacokinetic profile of LY3437943 was performed on 47 healthy participants (ClinicalTrials.gov, NCT03841630)
But language can create confidence before the evidence actually exists
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Gas chromatographyMS studies on urine samples have also been carried out by groups both in the US and Europe in rapid succession between 2012 and 2014
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