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Methodologically, GHK-Cu research has used cell-culture systems (primarily fibroblasts, keratinocytes, and dermal papilla cells), animal models (rodent wound-healing models predominantly), human clinical-research studies in cosmetic contexts, and analytical biochemistry approaches

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This resulted in increased splenic iron sequestration, diminished duodenal iron absorption and, consequently, decreased serum and tissue iron content accompanied by attenuation of oxidative stress (63,64)

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