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"We have many previous examples of how nutritional supplements widely available over the counter and unregulated by the Food and Drug Administration - for example, omega-3 fatty acids or various herbal substances - are touted as panaceas for you-name-it, and then don't pan out," she said

a Treatment success means 50% reduction in pain intensity during the daytime or nighttime or an improvement in pain and sleep of 6 in the PGIC score

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Theres a rebound effect that goes far beyond weight and Al-Aly says that there is a danger that could put people at risk of cardiac events