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From an evolutionary perspective, the activation of the ACTH/HPA axis and sympathetic spinal system, along with the diminished function of the prefrontal cortex, results in a diminished ability to seek and experience pleasure, reduced food intake, decreased sexual activity, and sleep apnea

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After initiation of WEGOVY, observe patients carefully for signs and symptoms of acute pancreatitis, which may include persistent or severe abdominal pain (sometimes radiating to the back), and which may or may not be accompanied by nausea or vomiting

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doi: 10.3390/cancers11070957