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The nanoparticles of silibinin exhibited antioxidant effects against intracellular oxidative stress by upregulating the Nrf2/ARE pathway, reducing ROS, modulating antioxidant enzyme responsiveness, and inhibiting downstream pathways of mitochondrial damage (Ding et al., 2022)

Li X, Wang D, Zhang J, Pan W

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According to the authors, the findings are more likely to reflect the physiological changes accompanying significant weight loss, including reduced calorie intake and potential nutritional deficiencies, than a direct effect of GLP-1 medicines on hair follicles