Characteristics of the Ipamorelina Key La Reina de la Selectividad (Su Gran Ventaja): Old GHRPs (such as GHRP-6 or GHRP-2) were potent, but sucios: they greatly increased hambre (ghrelin), cortisol (stress) and prolactin (which could cause secondary sexual effects)
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Why the study is misleading - The GLP1 group was dominated by older drugs like liraglutide and dulaglutide - The newer, more effective agents (semaglutide and tirzepatide) were barely included - Surgical patients were healthier and more motivated by design/screening, while the GLP1 group had more comorbidities and worse adherence - Treatment timelines did not align, so the comparison was not apples-to-apples - Risks were softened: 7% of surgical patients experienced serious complications, and nearly 1 in 200 died within 90 days So while the paper makes surgery look superior, what it really shows is surgery at its best compared to GLP1s at their weakest
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Use the dataset to benchmark suppliers and monitor regulatory activity where available
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