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A total of 44 subjects (22 Japanese and 22 Caucasian) were planned to be randomized to semaglutide 1.0 mg ( n = 8), semaglutide 0.5 mg ( n = 8), placebo 0.5 mg ( n = 3), or placebo 1.0 mg ( n = 3)
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Pre-treatment assessment should include: Comprehensive medical history : Specifically enquiring about previous pancreatitis, gallstone disease, alcohol consumption, and family history of pancreatic disorders Baseline investigations : HbA1c (for diabetes patients), renal function, lipid profile (including triglycerides), and liver function tests Consideration of risk factors : Assessment for gallstone disease in symptomatic patients or those with relevant history
