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Forty five years later, his concept of targeted therapy was first demonstrated in the form of an ADC, methotrexate conjugated to a leukemia cell-targeting antibody (Mathe et al., 1958)

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One notable finding from meta-analyses: cagrilintide demonstrated the lowest odds ratios for nausea, vomiting, and diarrhea when compared to other incretin-based therapies including semaglutide and tirzepatide