220 Indeed, adenoviral TFEB overexpression via tail vein injection significantly alleviated alcohol-induced pancreatitis by reducing tissue injury, lowering serum amylase and lipase levels, and partially preserving lysosomal proteins
In addition, in the pathogenesis of GERD, the abnormalities of digestive tract dynamics have gradually been emphasized by researchers, and it has been further found that the brain-gut peptide (neurotransmitter) in the brain-gut axis is not only related to visceral hypersensitivity, but also plays an important role in regulating gastrointestinal dynamics, and changes in the bacterial microbiome and its structure can stimulate the secretion of brain-gut peptide, so the emphasis on the bacterial microbiome in the future research will also provide therapeutic opportunities for the treatment of GERD
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Each experiment was independently repeated three times and data is presented as mean plus or minus standard deviation unless otherwise noted
Pan W, Jiang P, Zhao J, Shi H, Zhang P, Yang X, et al