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S.LiuG.RenzettiA.FarshiP.YangH.SoaveC.et al (2016)

For example, HIV entering the body through a mucosal surface will encounter few target cells in the form of activated CD4 + T cells initially and during a limited time period before its infectivity will be lost

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Considering these dual roles of mitochondria as instigators of innate immune activation via DAMPs release, and as regulators of immune cell fate via metabolism it is logical that therapeutically modulating mitochondrial function could have profound benefits for perioperative organ protection