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The effect is promising, but again, it came from a very small sample, so read it as "deserves more research" rather than "proven for everyone." Several small clinical trials on oral glutathione, some using doses similar to this product, have shown modest reductions in melanin index and improvements in skin brightness over 4 to 12 weeks

By reducing melanin synthesis, glutathione helps lighten the skin, reduce hyperpigmentation, and create a more uniform skin tone

In addition to the role of the NOS enzymes in generating NO, S-nitrosylation of proteins involves enzymes called SNO synthases and tansnitrosylases

A glutathione injection involves administering the antioxidant directly into the bloodstream