They are generally safe and very effective if you have struggled to lose weight through lifestyle change and need to lose a significant amount about 5-15% of your body weight
Common tapering protocols reduce doses by 25% every 2 to 4 weeks, though individual variations exist
It does not significantly affect cortisol, prolactin, or acetylcholine levels, thus reducing the risk of unwanted side effects
Keep an updated list of all your medications and review it with your healthcare team
In REDEFINE 1 , a 68-week, Phase 3a, multicenter, double-blind, placebo- and active-controlled trial, 3,417 adults with overweight or obesity but without diabetes were randomized to CagriSema (cagrilintide 2.4 mg + semaglutide 2.4 mg), semaglutide 2.4 mg, cagrilintide 2.4 mg, or placebo
By dampening this response, semaglutide helps to keep blood sugar levels more stable and reduces the risk of dangerous blood sugar spikes and crashes