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Yki-Jarvinen H (2007) ADOPT: lessons from comparison of glycemic durability of rosiglitazone, metformin, or glyburide monotherapy

On average, participants in clinical trials lost 5 to 10% of their starting weight

Health-Related Quality of Life Health-related quality of life (HRQoL) was not assessed in Study 1419 or its predecessors

When it expires the industry calls this the loss of exclusivity, or LOE other companies can legally make and sell copies, called generics

It is effective in treating a range of mental health conditions, including depression, OCD, panic disorder, social anxiety disorder, PTSD, and PMDD

This review comprehensively summarizes the role of mitophagy in metabolic diseases, the effects of different types of exercise on mitophagy, and the potential mechanisms of exercise-regulated mitophagy intervention in metabolic diseases, providing new insights for basic and clinical research on exercise intervention for preventing and treating metabolic diseases