(c) Immunometabolic crosstalk, discussing the complex interactions among local immune signaling, metabolic pathways, and ferroptosis within the inflammatory microenvironment of osteoarthritic joints
Recently, more CSF biomarkers reflecting other biological processes in AD have emerged, such as axonal injury and synaptic dysfunction (NfL, neurogranin (NG), synaptosomal-associated protein 25, visinin-like protein 1), 366,367,372 neuroinflammation (TREM2, YKL40, S100B, glial fibrillary acidic protein (GFAP)), 371,376,377,378 changes in neurotrophic protein levels (BDNF and NGF), 379 BBB disruption (soluble platelet-derived growth factor receptor-), 380 and metabolic changes (sphingomyelin, ceramide, fatty acid-binding protein 3, ubiquitin C-terminal hydrolase L1)
Yang, P
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