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Here's what I see work consistently in clinical practice: Protein-forward meals : Consuming 25-30g protein at breakfast stimulates GLP-1 release more effectively than carbohydrate-heavy meals [5] Soluble fiber : Particularly from sources like psyllium husk, chia seeds, and legumesthese feed beneficial gut bacteria that produce short-chain fatty acids, which trigger GLP-1 secretion [6] Omega-3 fatty acids : EPA and DHA from fish oil have been shown to increase GLP-1 production in several clinical trials [7] The concept of supplements that act like GLP-1 is marketing-speak for products containing these researched ingredients
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Glucagon and GLP-1 inhibit food intake and increase c-fos expression in similar appetite regulating centres in the brainstem and amygdala
This raises an important clinical question: if cardiometabolic risk is present, should GLP-1 therapy be considered even in patients who do not meet traditional BMI thresholds
Methylcobalamin is a biologically active form and so is more natural