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giving a prevalence of pathogenic MC4R mutations of 1.4% ( n = 32/2,291) in adults with obesity in the SURMOUNT-1 study (Extended Data Table 1)

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The group preprotected by LALPVYN showed an increase in GSH-Px enzyme activity compared to the damage group, and the GSH-Px enzyme activity after treatment with LALPVYN was 42.72 1.36, 50.93 1.25, and 58.72 1.36 Umg/Pro

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others exclude anti-obesity meds BCBS Federal Employee Program (FEP) Covered with PA BMI 30 or 27 with comorbidity