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The mechanisms of action are fundamentally different: GLP-1 agonists are synthetic or modified peptides designed to mimic incretin hormones and directly stimulate specific cellular receptors, while allulose is a simple sugar that undergoes passive absorption and excretion

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Research indicates that GLP-1 also has significant effects on cardiovascular function, including the modulation of heart rate and blood pressure, which further underscores its therapeutic potential beyond glycemic control [41]