The methodology is all about following a lectin-free diet and cutting out certain foods like whole grains, beans, dairy, legumes, and certain vegetables
Clinical trials show Retatrutide alone produces 24.2% average weight loss at 48 weeks, while intermittent fasting contributes an additional 1-4% reduction in baseline weight
The closest thing to a consensus datapoint remains Novos own guidance that the combined pricing impact will be low single digit negative for 2026 growth
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