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The compound was selected from a series of quinolinium-based molecules studied for cell permeability, enzyme selectivity and inhibition of NNMT

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Cancer-cell metabolism studies NNMT is overexpressed in several cancer cell lines, and 5-Amino-1MQ has been used in vitro to characterise its role in tumour metabolism

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Peptides are typically well-tolerated, but side effects can occur, especially if taken incorrectly or from unregulated sources