Tissue-specific peptide processing occurs through prohormone convertases that produce glucagon in the pancreas and GLP-1 and GLP-2 in the intestine 2
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doi:10.1080/07315724.1999.10718845
30 RabenMS
Emerging dual agonists, such as survodutide and cotadutide, which target GLP-1 and glucagon receptors, are being explored for treating metabolically associated fatty liver disease and may also address fatty kidney, a key factor in CKD related to visceral obesity [48]