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These can lead to neurodegenerative disorders like multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), Alzheimers disease (AD), Parkinsons disease (PD) (130)

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This imbalance compromises cellular equilibrium and initiates inflammation, which is necessary for immune defense

Serine is metabolized to glycine with subsequent methylation to form sarcosine (methylglycine) which was elevated in ME/CFS

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(2) cardiorespiratory fitness (peak oxygen consumption normalized to fat-free mass)